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Buchholz finished the game with 115 pitches, allowing Francona to escape what would have been an unpleasant decision to remove a pitcher from the game in which he was throwing a no-hitter.Buchholz' no-hitter was the third of a record-setting four caught by Jason Varitek.
On August 20, as the Red Sox were trying to sweep the Orioles, the team that Buchholz had no-hit the preceding year, he gave up a 4–0 lead by allowing three runs in the second inning and two more in the third. In his previous start, he had only lasted three innings.
He threw 115 pitches, struck out nine, walked three, and hit Nick Markakis.